Entamoeba histolytica detection refers to laboratory tests used to identify the presence of *Entamoeba histolytica*, the parasite responsible for amebiasis. These tests can include stool microscopy to detect cysts or trophozoites, antigen tests, and PCR (polymerase chain reaction) for genetic material. Additionally, blood tests measuring specific antibodies (IgG or IgM) can help indicate past or current infection. Detecting *E. histolytica* is crucial for diagnosing amebiasis, a condition that can cause symptoms ranging from mild gastrointestinal discomfort to severe colitis or liver abscesses.