Chromosome Analysis by Amniotic Fluid is a prenatal test that examines the chromosomes in a sample of amniotic fluid, which is the fluid surrounding a developing fetus. This test is typically performed through amniocentesis, where a small amount of amniotic fluid is collected and analyzed for chromosomal abnormalities such as Down syndrome (trisomy 21), trisomy 18, or other genetic disorders. It provides valuable information about the fetus’s genetic health and is commonly recommended for women with advanced maternal age or other risk factors for genetic conditions.