Hemoglobin Electrophoresis (HPLC) is a laboratory test used to identify different types of hemoglobin in the blood. It separates hemoglobin variants based on their electrical charge and size, helping diagnose inherited blood disorders like sickle cell disease , thalassemia , and other hemoglobinopathies.

The test is particularly useful in detecting abnormal hemoglobin types, which can cause anemia or other related conditions. It is performed using high-performance liquid chromatography (HPLC), a precise and accurate method.