The Anti-dsDNA Antibody, IFA test uses a specialized technique called indirect immunofluorescence to detect antibodies against double-stranded DNA (dsDNA). This test is commonly used to diagnose systemic lupus erythematosus (SLE), as elevated levels of anti-dsDNA antibodies are strongly associated with the disease. The IFA method involves using fluorescent dyes to highlight antibodies, allowing for precise detection. A blood sample is required for this test, which helps assess disease activity and monitor the progression of lupus.