Factor II (Prothrombin) Mutation Detection is a genetic test used to identify mutations in the prothrombin gene (F2), specifically the G20210A mutation. This mutation increases the risk of developing abnormal blood clots, a condition known as thrombophilia. The test is commonly used to assess an individual’s genetic predisposition to clotting disorders, particularly in cases of unexplained venous thromboembolism (blood clots in veins), such as deep vein thrombosis (DVT) or pulmonary embolism (PE). Identifying this mutation can help guide treatment and preventive measures to manage clotting risks.