The Total Cholesterol, Serum test measures the overall cholesterol levels in a patient’s blood, including both high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol, as well as very-low-density lipoprotein (VLDL). It is used to assess the risk of cardiovascular diseases, such as heart attack or stroke. Elevated total cholesterol levels may indicate an increased risk, while low levels may suggest other health issues. This test is commonly part of routine health screenings to monitor lipid health and guide preventive care.